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Article

Genetic polymorphisms in the ITPKC gene and cervical squamous cell carcinoma risk.

Cancer immunology, immunotherapy : CII - 1 Nov 2012

Yang Yuh-Cheng, Chang Tzu-Yang, Chen Tze-Chien, Chang Shih-Chuan, Chen Wei-Fang, Chan Hui-Wen, Lin Wen-Shan, Wu Fu-Ting, Lee Yann-Jinn

Abstract excerpt

Cervical cancer is caused primarily by infection with oncogenic types of human papillomavirus (HPV). However, HPV infection alone is not sufficient for the progression to cervical cancer. Host immunogenetic factors may involve in the development of this disease. Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is recently shown to act as a negative regulator of T-cell activation. We aim to study if polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22610085
DOI: 10.1007/s00262-012-1280-y
PMCID: PMC11029099

Genes

ITPKC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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