Article
Association of CD28 gene polymorphism with cervical cancer risk in a Chinese population.
International journal of immunogenetics - 1 Feb 2011
Chen X, Li H, Qiao Y, Yu D, Guo H, Tan W, Lin D
Abstract excerpt
Human papilloma virus plays a causal role in cervical carcinogenesis. However, only a small portion of infected individuals develop cervical cancer. Host genetic factors may confer susceptibility to this disease. CD28 participates in the maintenance of immune homeostasis as an important positive co-stimulatory molecule. Allelic variation of immuno-modulatory genes may be associated with alteration in immune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
