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Inhibitor of vasculogenic mimicry restores sensitivity of resistant melanoma cells to DNA-damaging agents.

Melanoma research - 1 Feb 2017

Vartanian Amalia, Baryshnikova Maria, Burova Olga, Afanasyeva Dariya, Misyurin Vsevolod, Belyаvsky Alexander, Shprakh Zoya

Abstract excerpt

The increasing incidence of melanoma makes this cancer an important public health problem. Therapeutic resistance is still a major obstacle to the therapy of patients with metastatic melanomas. The aim of this study was to develop the melanoma cell line resistant to DNA-alkylating agents and to elucidate the mechanisms involved in acquired drug resistance. We established a unique melanoma subline Mel MeR...

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PMID: 27776018
DOI: 10.1097/CMR.0000000000000308

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PRAME

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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