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Article

Therapeutic targeting of anoikis resistance in cutaneous melanoma metastasis

26 Apr 2023

Abstract excerpt

The acquisition of resistance to anoikis, the cell death induced by loss of adhesion to the extracellular matrix, is an absolute requirement for the survival of disseminating and circulating tumour cells (CTCs), and for the seeding of metastatic lesions. In melanoma, a range of intracellular signalling cascades have been identified as potential drivers of anoikis resistance, however a full understanding of the...

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Share to Cutaneous Melanoma Detection and Management
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37181747
DOI: 10.3389/fcell.2023.1183328

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