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Article

Efficient mutagenesis by CRISPR/Cas system during meiotic maturation of porcine oocytes.

The Journal of reproduction and development - 16 Feb 2017

Onuma Asuka, Fujii Wataru, Sugiura Koji, Naito Kunihiko

Abstract excerpt

Genome editing using the CRISPR/Cas system can induce mutations with high efficiency, and allows easier production of genome-modified animals than that offered by the conventional method where embryonic stem cells are used. However, studies using CRISPR/Cas systems have been mostly limited to proliferating somatic cells and pronuclear-stage fertilized eggs. In contrast, the efficiency of a CRISPR/Cas system in...

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Identifiers

PMID: 27773884
DOI: 10.1262/jrd.2016-094
PMCID: PMC5320429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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