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Article

Alterations of TRIM21-mRNA expression during monocyte maturation.

Immunobiology - 1 Mar 2017

Lenart Marzena, Rutkowska-Zapała Magdalena, Szatanek Rafał, Węglarczyk Kazimierz, Stec Małgorzata, Bukowska-Strakova Karolina, Gruca Anna, Czyż Jarosław, Siedlar Maciej

Abstract excerpt

Tripartite motif-containing protein 21 (TRIM21) play a dual role in the cytoplasm of the cells where it facilitates destruction of some antibody-coated viruses and some bacteria, and initiates synthesis of proinflammatory cytokines. Macrophages and CD16+ monocyte subset can particularly participate in a proinflammatory response caused by viral infection, however, the molecular mechanisms underlying these...

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Source

Identifiers

PMID: 27773663
DOI: 10.1016/j.imbio.2016.10.016

Genes

TRIM21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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