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Article

Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson's disease.

Journal of the neurological sciences - 15 Nov 2016

Gatto Nicole M, Paul Kimberly C, Sinsheimer Janet S, Bronstein Jeff M, Bordelon Yvette, Rausch Rebecca, Ritz Beate

Abstract excerpt

We and others have suggested that vitamin D receptor gene (VDR) polymorphisms influence susceptibility for Parkinson's disease (PD), Alzheimer's disease (AD), mild cognitive impairment (MCI) or overall cognitive functioning. Here we examine VDR polymorphisms and cognitive decline in patients with PD. Non-Hispanic Caucasian PD patients (n=190) in the Parkinson Environment Gene (PEG) study were successfully...

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Antiparkinson Agents
Cognitive Dysfunction
Educational Status
Gene-Environment Interaction
Longitudinal Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mental Status Schedule

Receptors, Calcitriol

Regression Analysis

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Identifiers

PMID: 27772736
DOI: 10.1016/j.jns.2016.09.013
PMCID: PMC5325129

Genes

VDR

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