Article
Lack of association between HLA-G 14-bp polymorphism and systemic lupus erythematosus in a Han Chinese population.
Lupus - 1 Dec 2009
Wu F-X, Wu L-J, Luo X-Y, Tang Z, Yang M-H, Xie C-M, Liu N-T, Zhou J-G, Guan J-L, Yuan G-H
Abstract excerpt
HLA-G is a non-classical HLA-class Ib molecule with multiple immunoregulatory properties. A 14-bp insertion/deletion polymorphism in the HLA-G gene has been suggested to influence the expression of HLA-G and to associate with certain pathological conditions, including autoimmune diseases. We investigated the influence of the 14-bp insertion/deletion polymorphism in the HLA-G gene on disease susceptibility in...
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