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Article

Impact of NOTCH1 polymorphisms on liver cancer in a Chinese Han population.

Cell cycle (Georgetown, Tex.) - 1 May 2023

Wang Baofeng, Ma Xiaobin, Zhang Wenjie, Li Liang, Zan Ying, Zhan Jianshui, Guo Xufeng, Lei Ming, Ma Hongbing

Abstract excerpt

NOTCH1, a member of the Notch family, is up-expression in advanced liver cancer (LC) patients and is associated with tumor sizes, tumor stage, metastasis, and invasion. A few studies have discovered the contribution of NOTCH1 variants to LC risk. Our purpose was to assess the relationship of NOTCH1 rs10521, rs2229971, and rs4489420 to LC risk. We enrolled 709 LC patients and 708 healthy controls. Genotyping was...

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Identifiers

PMID: 36951273
DOI: 10.1080/15384101.2023.2189766
PMCID: PMC10081089

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