Article
Association of genetic variations in GNB1 with response to peginterferon plus ribavirin therapy for chronic hepatitis C in a Chinese population in Taiwan.
BMC gastroenterology - 22 Nov 2012
Lim Yun-Ping, Tsai Fuu-Jen, Liao Wen-Ling, Tien Ni, Hung Dong-Zong, Peng Cheng-Yuan, Wan Lei
Abstract excerpt
BACKGROUND: The aim of this study was to evaluate whether polymorphisms in the guanine nucleotide binding (G protein), beta polypeptide 1 (GNB1) gene are associated with a rapid virological response (RVR) among HCV genotype 1 (HCV-1) and 2 (HCV-2) infected patients receiving peginterferon plus ribavirin treatment (PEG-IFNα-RBV). METHODS: We analyzed the association between RVR to PEG-IFNα-RBV therapy and 4...
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