Polymorphism of the complement 5 gene is associated with large artery atherosclerosis stroke in Chinese patients.

doi:10.1590/0004-282X20160139

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Article

Polymorphism of the complement 5 gene is associated with large artery atherosclerosis stroke in Chinese patients.

Arquivos de neuro-psiquiatria - 1 Nov 2016

Wu Hui, Weng Yingfeng, Zheng Lan, Li Huanyin, Gong Qi, Fu Yi, Zhao Jing

Abstract excerpt

METHODS: C5 rs17611 genetic variants were investigated in 494 IS patients and 330 control individuals .Ischemic stroke was classiﬁed into subtypes and patients were assessed 90 days post-stroke with the modified Rankin Scale to determine stroke outcome. RESULTS: The presence of C5 polymorphism was associated with the incidence of large artery atherosclerosis (LAA)-subtype IS (n =2 00; p = 0.031), which even...

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PMID: 27901252
DOI: 10.1590/0004-282X20160139

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