Article
Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay.
Clinical chemistry - 1 Jan 2009
Greisenegger Stefan, Zehetmayer Sonja, Bauer Peter, Endler Georg, Ferrari Julia, Lang Wilfried, Janisiw Michael, Steiner Lori, Cheng Suzanne, Lalouschek Wolfgang, Mannhalter Christine
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of these SNP results have not been replicated, however, and metaanalyses of the effects of inflammation-related genes are rare. We investigated 49 SNPs in 34 genes previously reported to be related to inflammation in our study. We tested 459 patients with acute ischemic...
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