Genetic variation in complement component C3 shows association with ischaemic stroke.

doi:10.1111/j.1468-1331.2011.03377.x

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Article

Genetic variation in complement component C3 shows association with ischaemic stroke.

European journal of neurology - 1 Oct 2011

Olsson S, Stokowska A, Holmegaard L, Jood K, Blomstrand C, Pekna M, Jern C

Abstract excerpt

BACKGROUND AND PURPOSE: The aim of this study was to investigate whether genetic variation at the third complement component (C3) locus is associated with ischaemic stroke (IS). METHODS: The Sahlgrenska Academy Study on Ischaemic Stroke comprises 844 patients with IS, and 668 healthy controls. Sixteen SNPs were analyzed. RESULTS: Two SNPs, rs2277984 and rs3745565, showed a significant association with overall IS....

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PMID: 21414106
DOI: 10.1111/j.1468-1331.2011.03377.x

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