Article
Frequencies of alpha4 A3061G variants and identification of three new variants of the human integrin alpha4-subunit.
Molecular immunology - 1 May 2003
Heymann G A, Kiesewetter H, Salama A
Abstract excerpt
Human integrin alpha4beta1 (VLA-4) is thought to play a key role in immune responses. Only two variants of alpha4-subunit (alpha4-tex and alpha4-mas) have been described until now, and the information regarding these variants is scanty. In this study, we measured the frequency of both variants in healthy blood donors (n=252). Surprisingly, the frequency of alpha4-mas (3061G, 0.31) was lower than that of...
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