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Article

Variants in the CNR1 gene predispose to headache with nausea in the presence of life stress.

Genes, brain, and behavior - 1 Mar 2017

Juhasz G, Csepany E, Magyar M, Edes A E, Eszlari N, Hullam G, Antal P, Kokonyei G, Anderson I M, Deakin J F W, Bagdy G

Abstract excerpt

One of the main effects of the endocannabinoid system in the brain is stress adaptation with presynaptic endocannabinoid receptor 1 (CB1 receptors) playing a major role. In the present study, we investigated whether the effect of the CB1 receptor coding CNR1 gene on migraine and its symptoms is conditional on life stress. In a cross-sectional European population (n = 2426), recruited from Manchester and Budapest,...

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Source

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Identifiers

PMID: 27762084
DOI: 10.1111/gbb.12352
PMCID: PMC5347942

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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