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Article

Variations in the cannabinoid receptor 1 gene predispose to migraine.

Neuroscience letters - 18 Sept 2009

Juhasz Gabriella, Lazary Judit, Chase Diana, Pegg Emma, Downey Darragh, Toth Zoltan G, Stones Kathryn, Platt Hazel, Mekli Krisztina, Payton Antony, Anderson Ian M, Deakin J F William, Bagdy Gyorgy

Abstract excerpt

In animal models endogenous cannabinoids have an inhibitory effect on trigeminovascular activation through the cannabinoid receptor 1 (CB1), although there is no evidence of the potential role of CB1 in human migraine. In this study we applied single marker association and haplotypic trend regression analysis to investigate the relationship between the CB1 gene (CNR1) and headache with migraine symptoms (nausea,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19539700
DOI: 10.1016/j.neulet.2009.06.021

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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