Article
The framework for population epigenetic study.
Briefings in bioinformatics - 1 Jan 2018
Zhao Linna, Liu Di, Xu Jing, Wang Zhaoyang, Chen Yang, Lei Changgui, Li Ying, Liu Guiyou, Jiang Yongshuai
Abstract excerpt
At present, understanding of DNA methylation at the population level is still limited. Here, we first extended the classical framework of population genetics, such as single nucleotide polymorphism allele frequency, linkage disequilibrium (LD), LD block and haplotype, to epigenetics. Then, as an example, we compared the DNA methylation disequilibrium (MD) maps between HapMap CEU (Caucasian residents of European...
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