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Article

Genes with stable DNA methylation levels show higher evolutionary conservation than genes with fluctuant DNA methylation levels.

Oncotarget - 24 Nov 2015

Zhang Ruijie, Lv Wenhua, Luan Meiwei, Zheng Jiajia, Shi Miao, Zhu Hongjie, Li Jin, Lv Hongchao, Zhang Mingming, Shang Zhenwei, Duan Lian, Jiang Yongshuai

Abstract excerpt

Different human genes often exhibit different degrees of stability in their DNA methylation levels between tissues, samples or cell types. This may be related to the evolution of human genome. Thus, we compared the evolutionary conservation between two types of genes: genes with stable DNA methylation levels (SM genes) and genes with fluctuant DNA methylation levels (FM genes). For long-term evolutionary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26515589
DOI: 10.18632/oncotarget.5504
PMCID: PMC4741891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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