Article
A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility.
European journal of human genetics : EJHG - 1 Jan 2016
Gupta Aditi, Juyal Garima, Sood Ajit, Midha Vandana, Yamazaki Keiko, Vich Vila Arnau, Esaki Motohiro, Matsui Toshiyuki, Takahashi Atsushi, Kubo Michiaki, Weersma Rinse K, Thelma B K
Abstract excerpt
The first ever genome-wide association study (GWAS) of ulcerative colitis in genetically distinct north Indian population identified two novel genes namely CFB and SLC44A4. Considering their biological relevance, we investigated allelic/genetic heterogeneity in these genes among ulcerative colitis cohorts of north Indian, Japanese and Dutch origin using high-density ImmunoChip case-control genotype data....
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