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Article

Suppression of skin tumorigenesis in CD109-deficient mice.

Oncotarget - 13 Dec 2016

Sunagawa Masaki, Mii Shinji, Enomoto Atsushi, Kato Takuya, Murakumo Yoshiki, Shiraki Yukihiro, Asai Naoya, Asai Masato, Nagino Masato, Takahashi Masahide

Abstract excerpt

CD109 is a glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed in several types of human cancers, particularly squamous cell carcinomas. We previously reported that CD109-deficient mice exhibit epidermal hyperplasia and chronic skin inflammation. Although we found that CD109 regulates differentiation of keratinocytes in vivo, the function of CD109 in tumorigenesis remains unknown. In this...

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Identifiers

PMID: 27756876
DOI: 10.18632/oncotarget.12653
PMCID: PMC5347736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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