Article
Quantification of epidermal growth factor receptor (EGFR) mutation may be a predictor of EGFR-tyrosine kinase inhibitor treatment response.
Thoracic cancer - 1 Nov 2016
Park Ha Young, Oh Hyung Joo, Kim Ki-Hyun, Kim Tae-Ok, Park Cheol-Kyu, Shin Hong-Jun, Lim Jung-Hwan, Kwon Yong-Soo, Oh In-Jae, Kim Yu-Il, Lim Sung-Chul, Kim Young-Chul, Choi Yoo-Duk
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) gene mutation is a reliable predictive factor for response to EGFR-tyrosine kinase inhibitors (TKIs). The quantified EGFR value may also predict response and survival within an EGFR mutated group. METHODS: We conducted a retrospective study of 836 lung cancer patients. The patient sample was divided into two groups based on the mean delta cycle threshold (∆Ct)...
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