Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NK receptor interactions with MHC class I molecules in pregnancy.

Seminars in immunology - 1 Dec 2008

Trowsdale John, Moffett Ashley

Abstract excerpt

Both HLA class I molecules and their receptors on Natural Killer cells, the KIR molecules, are highly polymorphic. It is generally believed that this variation is driven in response to the role of these receptors and counter-receptors in resistance to disease. Uterine NK cells are the major maternal leukocyte population present within the decidua, and they express KIR2D receptors for HLA-C, the only polymorphic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Communicable Diseases
Share to Genetic Variation
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Pregnancy

Share to Pregnancy Complications

Share to Receptors, KIR

Share to Reproductive System and Pregnancy

Share to Trophoblasts

Source

Identifiers

PMID: 18656382
DOI: 10.1016/j.smim.2008.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NK receptor interactions with MHC class I molecules in pregnancy.PMID 18656382Read ↗

Killer Ig-Like Receptor Expression in Uterine NK Cells Is Biased toward Recognition of HLA-C and Alters with Gestational AgeSemantic proximity Read ↗

The role of KIR and HLA interactions in pregnancy complicationsSemantic proximity Read ↗

Pregnancy immunogenetics: NK cell education in the womb?Semantic proximity Read ↗

Killer immunoglobulin-like receptors (KIRs) and HLA-C allorecognition patterns implicative of dominant activation of natural killer cells contribute to recurrent miscarriagesSemantic proximity Read ↗

NK Cells and TrophoblastsSemantic proximity Read ↗

Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation.Semantic proximity Read ↗

Immunity at maternal–fetal interface: KIR / HLA (Allo)recognition*Semantic proximity Read ↗

The effect of pregnancy on the uterine NK cell KIR repertoireSemantic proximity Read ↗

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.Semantic proximity Read ↗

Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention.Semantic proximity Read ↗

Recurrent Abortion and the Involvement of Killer-Cell Immunoglobulin-like Receptor (KIR) Genes, Activated T Cells, NK Abnormalities, and Cytokine ProfilesSemantic proximity Read ↗

Expression of killer cell inhibitory receptors on human uterine natural killer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.