Article
Cross-validation of clinical characteristics and treatment patterns associated with phenotypes for lithium response defined by the Alda scale.
Journal of affective disorders - 15 Jan 2017
Scott Jan, Geoffroy Pierre Alexis, Sportiche Sarah, Brichant-Petit-Jean Clara, Gard Sebastien, Kahn Jean-Pierre, Azorin Jean-Michel, Henry Chantal, Etain Bruno, Bellivier Frank
Abstract excerpt
BACKGROUND: It is increasingly recognised that reliable and valid assessments of lithium response are needed in order to target more efficiently the use of this medication in bipolar disorders (BD) and to identify genotypes, endophenotypes and biomarkers of response. METHODS: In a large, multi-centre, clinically representative sample of 300 cases of BD, we assess external clinical validators of lithium response...
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