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Article

Phenotypic clustering of bipolar disorder supports stratification by lithium responsiveness over diagnostic subtypes.

Acta psychiatrica Scandinavica - 1 Aug 2024

Scott Katie, O'Donovan Claire, Brancati Giulio Emilio, Cervantes Pablo, Ardau Rafaella, Manchia Mirko, Severino Giovanni, Rybakowski Janusz, Tondo Leonardo, Grof Paul, Alda Martin, Nunes Abraham

Abstract excerpt

INTRODUCTION: The aim of this study was to determine whether the clinical profiles of bipolar disorder (BD) patients could be differentiated more clearly using the existing classification by diagnostic subtype or by lithium treatment responsiveness. METHODS: We included adult patients with BD-I or II (N = 477 across four sites) who were treated with lithium as their principal mood stabilizer for at least 1 year....

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Identifiers

PMID: 38643982
DOI: 10.1111/acps.13692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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