Article
A cross-sectional study to assess any possible linkage of C/T polymorphism in CYP17A1 gene with insulin resistance in non-obese women with polycystic ovarian syndrome.
The Indian journal of medical research - 1 Jun 2016
Banerjee Ushasi, Dasgupta Anindya, Khan Aparna, Ghosh Mrinal Kanti, Roy Pranab, Rout Jayanta Kumar, Roy Priyankar, Dhara Suparna
Abstract excerpt
BACKGROUND & OBJECTIVES: Insulin resistance (IR) is a major confounding factor in polycystic ovarian syndrome (PCOS) irrespective of obesity. Its exact mechanism remains elusive till now. C/T polymorphism in the -34 promoter region of the CYP17 gene is inconsistently attributed to elucidate the mechanism of IR and its link to hyperandrogenemia in obese PCOS patients. In the present study we aimed to evaluate any...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
