Article
No association of the G972S polymorphism of the insulin receptor substrate-1 gene with polycystic ovary syndrome in lean PCOS women with biochemical hyperandrogenemia.
Archives of gynecology and obstetrics - 1 Jun 2010
Marioli Dimitra J, Koika Vasiliki, Adonakis George L, Saltamavros Alexandros D, Karela Anastasia, Armeni Anastasia K, Tsapanos Vasilios S, Decavalas George O, Georgopoulos Neoklis A
Abstract excerpt
PURPOSE: The aim of the present study was to determine the prevalence and association of the G972S polymorphism of the insulin receptor substrate-1 gene (IRS-1 G972S SNP) with polycystic ovary syndrome (PCOS) and insulin resistance-related traits in a distinct phenotypic group of lean PCOS women with biochemical hyperandrogenemia, excluding obesity, which is considered to be an aggravating parameter of insulin...
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