Article
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.
BMC medical genetics - 7 Apr 2006
Lin Ta-Chin, Yen Jui-Mei, Gong Kum-Bing, Kuo Tsung-Cheng, Ku Dong-Chi, Liang Shu-Fen, Wu Ming-Jiuan
Abstract excerpt
BACKGROUND: Insulin resistance and glucose dysmetabolism in polycystic ovary syndrome (PCOS) are related with the polymorphisms in the genes encoding the insulin receptor substrate (IRS) proteins, especially Gly972Arg/Ala513Pro polymorphism being reported to be associated with type-2 diabetes and PCOS. We intended to assess the prevalence of abnormal glucose tolerance (AGT) and insulin resistance in Taiwanese...
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