Article
Association of CYP17A1 gene -34T/C polymorphism with polycystic ovary syndrome in Han Chinese population.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2015
Li Li, Gu Zhen-Peng, Bo Qi-Mei, Wang Dong, Yang Xing-Sheng, Cai Guo-Hua
Abstract excerpt
PURPOSE: To investigate the influence of the cytochrome P450 17α (CYP17A1) gene -34T/C polymorphism in the pathogenesis of polycystic ovary syndrome (PCOS) in Han Chinese population. METHODS: Three-hundred eighteen patients with PCOS and 306 controls were recruited and the CYP17A1 -34T/C polymorphism was genotyped using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Furthermore,...
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