Article
Cancer cells acquire resistance to anticancer drugs: an update.
Biomedical journal - 1 Jan 2000
Lu Hsing-Pang, Chao Chuck C K
Abstract excerpt
The efficacy of cancer chemotherapy is often affected by the emergence of resistant can-cer cells. While biochemical and pharmaco-logical mechanisms have been proposed to ex-plain chemo-resistance, the genes involved in this process have not been fully identified. We previously used genomic DNA microarrays and quantitative RT-PCR to identify the genes associated with resistance to chemotherapeutic drugs,...
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