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Article

Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells.

International journal of oncology - 1 Dec 2016

El Khoury Flaria, Corcos Laurent, Durand Stéphanie, Simon Brigitte, Le Jossic-Corcos Catherine

Abstract excerpt

Colorectal cancer (CRC) is one of the most aggressive cancers worldwide. Several anticancer agents are available to treat CRC, but eventually cancer relapse occurs. One major cause of chemotherapy failure is the emergence of drug-resistant tumor cells, suspected to originate from the stem cell compartment. The aim of this study was to ask whether drug resistance was associated with the acquisition of stem...

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Identifiers

PMID: 27748801
DOI: 10.3892/ijo.2016.3725

Genes

ABCG2
EPHB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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