Article
Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation.
The Journal of rheumatology - 1 Jan 2017
Jansen Henning, Willenborg Christina, Lieb Wolfgang, Zeng Lingyao, Ferrario Paola Gloria, Loley Christina, König Inke R, Erdmann Jeanette, Samani Nilesh J, Schunkert Heribert
Abstract excerpt
OBJECTIVE: Inflammatory diseases, specifically rheumatoid arthritis (RA), are assumed to increase the risk of coronary artery disease (CAD). More recently, multiple single-nucleotide polymorphisms (SNP) associated with RA risk were identified. If causal mechanisms affecting risks of RA and CAD are overlapping, risk alleles for RA might also increase the risk of CAD. METHODS: Sixty-one SNP associating with RA in...
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