Article
Causal association between rheumatoid arthritis and risk of stroke: A Mendelian randomization study.
Clinical neurology and neurosurgery - 1 Sept 2024
Qiang Fuyong, Xuan Dan, Li Zhi, Chen Lanfang, Wang Li, Sheng Jun
Abstract excerpt
BACKGROUND: Active rheumatoid arthritis (RA) may damage vascular endothelial cells, thereby increasing the likelihood of adverse cardiovascular events. However, it is not yet clearly established whether RA also increases the risk of adverse cerebrovascular events, particularly stroke. OBJECTIVE: This study was designed to evaluate the likelihood of a causal association between RA and stroke. METHOD: A two-sample...
Topics
- Humans
- Arthritis, Rheumatoid
- Mendelian Randomization Analysis
- Stroke
- Genome-Wide Association Study
- Polymorphism, Single Nucleotide
- Risk Factors
- Genetic Predisposition to Disease