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Rheumatoid Arthritis and Cardio-Cerebrovascular Disease: A Mendelian Randomization Study

21 Oct 2021

Abstract excerpt

Significant genetic association exists between rheumatoid arthritis (RA) and cardiovascular disease. The associated mechanisms include common inflammatory mediators, changes in lipoprotein composition and function, immune responses, etc. However, the causality of RA and vascular/heart problems remains unknown. Herein, we performed Mendelian randomization (MR) analysis using a large-scale RA genome-wide...

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PMID: 34745219
DOI: 10.3389/fgene.2021.745224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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