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Article

Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp.

PLoS genetics - 1 Oct 2016

Liu Zhongle, Moran Gary P, Sullivan Derek J, MacCallum Donna M, Myers Lawrence C

Abstract excerpt

Filamentous growth is a hallmark of C. albicans pathogenicity compared to less-virulent ascomycetes. A multitude of transcription factors regulate filamentous growth in response to specific environmental cues. Our work, however, suggests the evolutionary history of C. albicans that resulted in its filamentous growth plasticity may be tied to a change in the general transcription machinery rather than...

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Identifiers

PMID: 27741243
DOI: 10.1371/journal.pgen.1006373
PMCID: PMC5065183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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