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Article

Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans.

PLoS genetics - 1 Apr 2018

Dunn Matthew J, Kinney Griffin M, Washington Pamela M, Berman Judith, Anderson Matthew Z

Abstract excerpt

Gene duplication facilitates functional diversification and provides greater phenotypic flexibility to an organism. Expanded gene families arise through repeated gene duplication but the extent of functional divergence that accompanies each paralogous gene is generally unexplored because of the difficulty in isolating the effects of single family members. The telomere-associated (TLO) gene family is a remarkable...

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PMID: 29630599
DOI: 10.1371/journal.pgen.1007326
PMCID: PMC5908203

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