Article
TFF1 gene single nucleotide polymorphism (rs3761376) and colorectal cancer risk.
Molecular biology reports - 1 Oct 2022
Shekarriz Ramin, Kochaki Nafiseh, Eslami-Jouibari Mohammad, Omrani-Nava Versa, Ahmadi Mohadeseh, Alizadeh-Navaei Reza
Abstract excerpt
INTRODUCTION: Trefoil Factor 1 (TFF1) is a secretory peptide with gastrointestinal protective functions. Abnormal TFF1 expression is reported in some cancers and functional promoter polymorphism in TFF1 is believed to be associated with risk of gastric cancer. We evaluated rs3761376 in a sample of Iranian patients with colorectal cancer. METHODS: Peripheral blood samples were taken from pathology confirmed cases...
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