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Article

miRNA polymorphisms and risk of gastric cancer in Asian population.

World journal of gastroenterology - 21 May 2014

Hua Hai-Bing, Yan Ting-Ting, Sun Qing-Min

Abstract excerpt

miRNAs are endogenous 19- to 25-nt noncoding RNAs that can negatively regulate gene expression by directly cleaving target mRNA or by inhibiting its translation. Recent studies have revealed that miRNA plays a significant role in gastric cancer development either as a tumor suppressor gene or oncogene. miRNA-single-nucleotide polymorphisms (SNPs), as a novel class of functional SNPs/polymorphisms, have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24914331
DOI: 10.3748/wjg.v20.i19.5700
PMCID: PMC4024780

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