Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary

5 Aug 2020

Abstract excerpt

We sequenced more than 52,500 single cells from embryonic day 11.5 (E11.5) postembryonic day 5 (P5) gonads and performed lineage tracing to analyze primordial follicles and wave 1 medullar follicles during mouse fetal and perinatal oogenesis. Germ cells clustered into six meiotic substages, as well as dying/nurse cells. Wnt-expressing bipotential precursors already present at E11.5 are followed at each...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prenatal Screening and Diagnostics
Share to Renal and related cancers
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32759216
DOI: 10.1073/pnas.2005570117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovaryPMID 32759216Read ↗

Escort-like somatic cells mediate early mouse fetal ovarian development but surface-derived Lgr5+ cells support primordial folliclesSemantic proximity Read ↗

Transcriptome Landscape Reveals Underlying Mechanisms of Ovarian Cell Fate Differentiation and Primordial Follicle AssemblySemantic proximity Read ↗

Single-cell roadmap of bovine oogenesis and somatic niche interactions during fetal ovarian developmentSemantic proximity Read ↗

ADAM10–Notch signaling governs the recruitment of ovarian pregranulosa cells and controls folliculogenesis in miceSemantic proximity Read ↗

Mouse Ovarian Germ Cell Cysts Undergo Programmed Breakdown to Form Primordial FolliclesSemantic proximity Read ↗

Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interactions during Primordial Follicle ActivationSemantic proximity Read ↗

Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice1Semantic proximity Read ↗

Transcriptomic signatures of WNT-driven pathways and granulosa cell-oocyte interactions during primordial follicle activationSemantic proximity Read ↗

Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in miceSemantic proximity Read ↗

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomicsSemantic proximity Read ↗

Comparative single-cell transcriptomic roadmap of mammalian fetal ovarian developmentSemantic proximity Read ↗

Single-cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.