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Article

The transcription factor GATA4 is required for follicular development and normal ovarian function.

Developmental biology - 1 Sept 2013

Efimenko Evgeni, Padua Maria B, Manuylov Nikolay L, Fox Shawna C, Morse Deborah A, Tevosian Sergei G

Abstract excerpt

Sex determination in mammals requires interaction between the transcription factor GATA4 and its cofactor FOG2. We have recently described the function of both proteins in testis development beyond the sex determination stage; their roles in the postnatal ovary, however, remain to be defined. Here, we use gene targeting in mice to determine the requirement of GATA4 and FOG2 in ovarian development and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23769843
DOI: 10.1016/j.ydbio.2013.06.004
PMCID: PMC4089064

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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