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Quantitative haplotyping of PCR products by nonsynchronous pyrosequencing with di-base addition.

Analytical and bioanalytical chemistry - 1 Nov 2016

Pan Rongfang, Xiao Pengfeng

Abstract excerpt

Molecular haplotyping is becoming increasingly important for studying the disease association of a specific allele because of its ability of providing more information than any single nucleotide polymorphism (SNP). Computational analysis and experimental techniques are usually performed for haplotypic determination. However, established methods are not suitable for analyzing haplotypes of massive natural DNA...

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PMID: 27734136
DOI: 10.1007/s00216-016-9936-7

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