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Article

The effect of BCG vaccination on macrophage phenotype in a mouse model of intranasal Mycobacterium bovis challenge.

Vaccine - 19 Jun 2020

Civello Alexander N, Spiropoulos John, Sánchez-Cordón Pedro J, Hicks Daniel J, Hogarth Philip J, Birch Colin, Núñez Alejandro

Abstract excerpt

In order to develop improved vaccinations against tuberculosis, it is essential to understand the effect of vaccination on the immune response, and to overcome the mechanisms by which mycobacteria regulate this immune response. In this study, we examine the effect of intradermal vaccination with Mycobacterium bovis bacille Calmette-Guèrin on macrophage phenotype following intranasal challenge with virulent...

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Identifiers

PMID: 32451209
DOI: 10.1016/j.vaccine.2020.05.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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