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Article

Molecular pathophysiology of myelodysplastic syndromes.

Annual review of pathology - 24 Jan 2013

Lindsley R Coleman, Ebert Benjamin L

Abstract excerpt

The clinicopathologic heterogeneity of myelodysplastic syndromes (MDS) is driven by diverse, somatically acquired genetic abnormalities. Recent technological advances have enabled the identification of many new mutations, which have implicated novel pathways in MDS pathogenesis, including RNA splicing and epigenetic regulation of gene expression. Molecular abnormalities, either somatic point mutations or...

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Identifiers

PMID: 22934674
DOI: 10.1146/annurev-pathol-011811-132436
PMCID: PMC3514602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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