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Connectome Disconnectivity and Cortical Gene Expression in Patients With Schizophrenia.

Biological psychiatry - 15 Mar 2017

Romme Ingrid A C, de Reus Marcel A, Ophoff Roel A, Kahn René S, van den Heuvel Martijn P

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified several common risk loci for schizophrenia (SCZ). In parallel, neuroimaging studies have shown consistent findings of widespread white matter disconnectivity in patients with SCZ. METHODS: We examined the role of genes in brain connectivity in patients with SCZ by combining transcriptional profiles of 43 SCZ risk genes identified by the recent...

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PMID: 27720199
DOI: 10.1016/j.biopsych.2016.07.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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