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Article

NADH dehydrogenase of Trypanosoma brucei is important for efficient acetate production in bloodstream forms.

Molecular and biochemical parasitology - 1 Jan 2017

Surve Sachin V, Jensen Bryan C, Heestand Meredith, Mazet Muriel, Smith Terry K, Bringaud Frédéric, Parsons Marilyn, Schnaufer Achim

Abstract excerpt

In the slender bloodstream form, Trypanosoma brucei mitochondria are repressed for many functions. Multiple components of mitochondrial complex I, NADH:ubiquinone oxidoreductase, are expressed in this stage, but electron transfer through complex I is not essential. Here we investigate the role of the parasite's second NADH:ubiquinone oxidoreductase, NDH2, which is composed of a single subunit that also localizes...

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Identifiers

PMID: 27717801
DOI: 10.1016/j.molbiopara.2016.10.001
PMCID: PMC5225879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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