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Redesigned and reversed: architectural and functional oddities of the trypanosomal ATP synthase

8 Feb 2021

Abstract excerpt

Mitochondrial F-type adenosine triphosphate (ATP) synthases are commonly introduced as highly conserved membrane-embedded rotary machines generating the majority of cellular ATP. This simplified view neglects recently revealed striking compositional diversity of the enzyme and the fact that in specific life stages of some parasites, the physiological role of the enzyme is to maintain the mitochondrial membrane...

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PMID: 33551002
DOI: 10.1017/s0031182021000202

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