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Article

A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.

The Journal of biological chemistry - 29 Apr 2005

Coustou Virginie, Besteiro Sébastien, Rivière Loïc, Biran Marc, Biteau Nicolas, Franconi Jean-Michel, Boshart Michael, Baltz Théo, Bringaud Frédéric

Abstract excerpt

Trypanosoma brucei is a parasitic protist responsible for sleeping sickness in humans. The procyclic stage of T. brucei expresses a soluble NADH-dependent fumarate reductase (FRDg) in the peroxisome-like organelles called glycosomes. This enzyme is responsible for the production of about 70% of t...

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Source

Identifiers

PMID: 15718239
DOI: 10.1074/jbc.M500343200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15718239-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.PMID 15718239Read ↗

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