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Article

FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence.

Alcoholism, clinical and experimental research - 1 Nov 2016

Spagnolo Primavera A, Ramchandani Vijay A, Schwandt Melanie L, Kwako Laura E, George David T, Mayo Leah M, Hillard Cecilia J, Heilig Markus

Abstract excerpt

BACKGROUND: A common single nucleotide polymorphism (C385A) in the human fatty acid amide hydrolase (FAAH) gene has been associated with decreased distress responses in healthy volunteers, but its role in psychiatric disorders remains unknown. Here, we obtained genotypes and carried out a secondary analysis of subjects from a trial of comorbid posttraumatic stress disorder (PTSD) and alcohol dependence (AD). We...

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Identifiers

PMID: 27716956
DOI: 10.1111/acer.13210
PMCID: PMC5748341

Genes

FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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