Article
Ascertainment bias from imputation methods evaluation in wheat.
BMC genomics - 4 Oct 2016
Brandariz Sofía P, González Reymúndez Agustín, Lado Bettina, Malosetti Marcos, Garcia Antonio Augusto Franco, Quincke Martín, von Zitzewitz Jarislav, Castro Marina, Matus Iván, Del Pozo Alejandro, Castro Ariel J, Gutiérrez Lucía
Abstract excerpt
BACKGROUND: Whole-genome genotyping techniques like Genotyping-by-sequencing (GBS) are being used for genetic studies such as Genome-Wide Association (GWAS) and Genomewide Selection (GS), where different strategies for imputation have been developed. Nevertheless, imputation error may lead to poor performance (i.e. smaller power or higher false positive rate) when complete data is not required as it is for GWAS,...
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