Article
The impact of autophagy on the development of senescence in primary tubular epithelial cells.
Cell cycle (Georgetown, Tex.) - 1 Nov 2016
Baisantry Arpita, Bhayana Sagar, Wrede Christoph, Hegermann Jan, Haller Hermann, Melk Anette, Schmitt Roland
Abstract excerpt
Autophagy and senescence are 2 distinct pathways that are importantly involved in acute kidney injury and renal repair. Recent data indicate that the 2 processes might be interrelated. To investigate the potential link between autophagy and senescence in the kidney we isolated primary tubular epithelial cells (PTEC) from wild-type mice and monitored the occurrence of cellular senescence during autophagy...
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