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Article

Endothelial autophagy and Endothelial-to-Mesenchymal Transition (EndoMT) in eEPC treatment of ischemic AKI.

Journal of nephrology - 1 Oct 2016

Patschan Daniel, Schwarze Katrin, Henze Elvira, Patschan Susann, Müller Gerhard Anton

Abstract excerpt

BACKGROUND: Autophagy enables cells to digest endogenous/exogenous waste products, thus potentially prolonging the cellular lifespan. Early endothelial progenitor cells (eEPCs) protect mice from ischemic acute kidney injury (AKI). The mid-term prognosis in AKI critically depends on vascular rarefication and interstitial fibrosis with the latter partly being induced by mesenchymal transdifferentiation of...

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Identifiers

PMID: 26289253
DOI: 10.1007/s40620-015-0222-0
PMCID: PMC5016542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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